Thanks to new transient surveys and advances in high-performance computing our knowledge on supernova explosion has tremendously increased in the past decade. To consolidate progress, it is important to make specialists in different aspects of supernova research aware of progress and challenges on other fronts. Together with Anders Jerkstrand (Max Planck Institute for Astrophysics Garching) and Bernhard Mueller (Monash University), I have co-organized the 660. Wilhelm und Else Heraeus Seminar “Supernovae – From Simulations to Observations and Nucleosynthetic Fingerprints”, which was held at Physikzentrum Bad Honnef from January 21 to 24, 2018. The seminar, generously funded by the Wilhelm und Else Heraeus Stiftung, brought together world-leading experts, early career researchers, and students. With over 60 participants from all over the world we discussed the physical modelling of stellar explosions, their nucleosynthesis, radiation transfer, and supernova observations to identify future opportunities at the intersection of these four different research fields.